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They promote the absorption of active substances through the skin (transdermal transport).

In general, the human body allows the drugs and active substances from dietary supplements to reach their destination - the place of action. There are shorter and faster pathways, but also pathways that are more lengthy and significantly slower. In addition, on the way to their destination, active substances may be subjected to adverse influences that may lead to their modification or degradation.

In order to act, the active substances must enter the bloodstream and be transported to the desired location by the cardiovascular system. The fastest route is to administer them directly into the cardiovascular system by intravenous injection or intravenous infusion. However, this is not practically possible in the case of daily application of nutritional supplements.

The simplest way is to take the nutritional supplements orally, i.e. by mouth. In this way, various tablets, dragees, capsules, solutions, drops, suspensions, emulsions, syrups or healthy drinks can be administered or taken.This form of taking and using nutritional supplements is very simple and, above all, very pleasant for everyone. The disadvantage is that the medicine can only enter the bloodstream after it has passed through the digestive tract to the liver, where it actually enters the blood via the portal vein. The passage of the drug through the gastrointestinal tract and the liver may lead to less or more conversion (metabolisation) of the active doses and therefore to a reduction in the efficacy or even to degradation and inactivation of the active substance. In much the same way (via the portal vein), a drug administered rectally (via the rectum) enters the blood.

For rapid and guaranteed application of the active substance, a transdermal therapeutic system is used, where the drug is administered through the skin. In this case, the active substance is administered in the form of a patch, cream, gel or spray, penetrates the skin and enters the bloodstream directly. For example, anti-nicotine preparations to help with smoking cessation, or patches or creams and gels for pain are also administered in this way.

The application of a spray form of active substances to the skin is one of the alternatives that is becoming and will become increasingly preferable to taking tablets or injecting them. When sprays are applied to the wrist or topically to the affected area, the active substances are absorbed transdermally into the bloodstream. This avoids exposure of the active substances to the environment in the mouth, or in the stomach or other parts of the digestive tract, and thus the risk of modification or degradation of the active substances. The skin provides a large surface area suitable for absorption. Absorption has been shown to be much faster in this case than when taken in tablet or capsule form.

Activstar has in its product portfolio sprays made with a special technology, which contributes to better absorption and effectiveness of the active ingredients.

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For example, ACTIV HAIR spray is used directly on the affected area, i.e. on the hair part of the scalp, and contributes to the strengthening of hair follicles and hair growth, limiting their weakening and hair loss.

ACTIV BODY spray has a regenerating and relaxing effect on the musculoskeletal system. The plant extracts contained in it have antibacterial, anti-inflammatory, anti-allergic and regenerative effects on the skin and individual parts of the musculoskeletal system. The preparation supplies the body with a number of useful substances such as antioxidants, minerals and vitamins. Applied to the affected area, it is quickly absorbed and leaves a pleasant sensation.

Another spray in the Activstar range is ACTIV MAGNESIUM. This spray supplies the body with magnesium - one of the most important minerals for the proper functioning of the human body.

ACTIV LIFE spray works to invigorate and refresh the body both physically and mentally. It contributes to the strengthening of potency, strengthens the sexual libido of men and women. It adds strength and energy in everyday life, acts on mental stimulation and helps to improve physical performance.

Very interesting is the spray ACTIV BOSWELLIA. The extract of frankincense (resin of the incense tree) has a strong anti-inflammatory effect and in the case of the skin, joints but also in other cases. In addition, it has strong disinfectant, antiviral and antibacterial effects. It also acts as a natural analgesic. It contributes to the proper functioning of the immune system, the digestive system and also the central nervous system, including the brain. It activates the lymphatic system and thus also counteracts cellulite. It slows down skin ageing and improves the appearance of scars and stretch marks.

ACTIV C - vitamin C in spray form has a positive effect on the vitality and regeneration of the body, when applied to the skin it contributes to its freshness and elasticity and triggers regenerative processes. The company offers it in two pleasant scents - citrus and lemongrass.

NANO SPRAY has a broad-spectrum use. It contains colloidal silver, which is considered a natural antibiotic. It also has antibacterial and disinfectant effects. It helps with abrasions, scratches, as well as infections of the throat, mucous membranes, eyes and ears.

All the sprays mentioned above are applied to the affected area (scalp, skin, sore joints, for muscle cramps...) where they are locally absorbed and act directly on the spot (ACTIV HAIR, ACTIV BODY, ACTIV NANO), or on the wrist (ACTIV LIFE), where they enter directly into the lymphatic system and blood capillaries, and from there into the whole body. ACTIV MAGNESIUM, ACTIV BOSWELLIA, ACTIV C sprays are applied on the wrist or directly on the place where they are supposed to act. ACTIV BOSWELLIA and ACTIV C sprays have an additional cosmetic effect - they act directly on the skin locally at the point of application and trigger regenerative processes in all skin layers in individual skin cells and contribute to slowing down skin ageing and its elasticity and freshness.

Literature sources:

  • Thomas BJ and Finnin BC. 2004. The transdermal revolution. Drug Discovery Today. 9(16), 697-703.
  • Walter JR and Xu S. 2015. Therapeutic transdermal drug innovation from 2000 to 2014: current status and outlook. Drug Discovery Today. 20(11), 1293-1299.
  • Naik A, Kalia YN and Guy RH. (2000). Transdermal drug delivery: overcoming the skin’s barrier function. Pharmaceutical Science & Technology Today. 3(9), 318-326.
  • Uttam KM, Bappaditya Ch, Fatin HBP. (2016) A Review on Transdermal Spray: Formulation Aspect. M J Pharma 1(1): 006
  • Ibrahim SA (2015) Spray-on transdermal drug delivery systems. Expert Opin Drug Deliv 12(2) 195-205
Elena - Púchov

I'm very excited and I'm going to share... The effect of the NO spray has been confirmed. Last year after heart surgery. Arrhythmia 206 pulses. We also discovered a multiarrhythmic heart during the operation. Well, today, after checking and using NO spray, NO drink, the results have improved. So wow effect and I continue and I'm satisfied

Elena - Púchov

Elena - Púchov
Helenka PP

This month I had my grandson on vacation and we were caught by a virus at the very beginning, so my helper was activ nano spray, which I sprayed into his nose and throat, boswellia for the throat and vitamin C. On the third day, the grandson was fine, but I she got it in full, so I increased the dose of vitamin C and activmineral and added Activ 3 and cordyceps to it. To make matters worse, our little baby broke her head, the first thing I took out of the bag was the nano spray, we immediately stopped the blood. So that's why my answer is simple, I have helpers at hand right away, a back commission and great people around me. Thank you for being.

Helenka PP

Lýdia

Activ AG spray helps me as soon as I feel something crawling on me – runny nose, vocal cords? Just spray it in the throat or nose. Barley, conjunctivitis? Sore ear from drafts or air conditioning? BUK in the ear. I also use it instead of nose drops. Great after deep cleansing of the skin – the skin is soothed in the morning. For any injuries – it works immediately.

Lýdia

Libor

After about a month of using Activ NO drinks, my wife's heart palpitations stopped and her heart rate, which was quite high, decreased. The varicose vein on my calf disappeared after using the NO drink and spraying the NO spray.

Libor

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